The Anqing MS4． 8 earthquake occurred on January 19，2011，and the epicenter lies in foreland deformation belt along the Yangtze River in Yangtze plate． After the earthquake，the field work team surveyed and summarized the building damage data，calculating intensity distribution， obtaining comparatively reliable intensity distribution graph． The focal mechanisms of main shock are calculated tentatively using digital seismic wave data in some provincial digital seismic networks based on the FOCMEC program，combing the first motion of P，SV and SH waves with their amplitude ratios． The comprehensive analysis of the major aftershock location result of Anhui seismic network，together with the focal region crust three-dimensional velocity structural images by the seismic tomographic technology，and the intensity distribution of elliptic long axis advantage direction reveals that NE trend Susong-Zongyang fault may be the causative fault of Anqing earthquake．