In this paper, we focused on earthquakes with Ms ≥7.0 in Chinese mainland from 1900 to 2012, calculated the lunisolar tidal coulomb failure stress on the seismic fault plane and got the tidal phase. With the help of Schuster＇s examination, a quantitative analysis was made about the correlation of strong earthquakes in the Chinese mainland with tidal coulomb failure stress. Research shows that of 57 strong earthquakes with focal mechanism solutions, over 71.9% took place within the tidal loading phase. The p value is 3.83%, demonstrating that strong earthquakes with Ms≥ 7.0 in Chinese mainland have a certain correlation with lunisolar tidal coulomb failure stress. In the active period, the p value is 41 56% , and 75.5% earthquakes occurred in the tidal loading phase zone. 50% earthquakes occurred in the quiescence period, indicating that strong earthquakes in the active period were obviously triggered with the tidal coulomb failure stress loading.