The Tancheng-Lujiang fault zone has great influence in eastern China． Studies have shown that the obvious signs of new activities exit in the segment from Xinyi to Wuhe of the Tancheng-Lujiang fault zone． In this paper，on the basis of the previous work，many seismological surveys have been made along the Tancheng-Lujiang fault zone． In the key sites the trenches have been excavated． Combined with the analysis of the seismic activities along the fault，the fault activity features and future seismic risks are discussed． Much first-hand information added in the paper can provide an important reference value for the study of large earthquake recurrence rule and the med- and long-term earthquake prediction of the segment from Xinyi to Wuhe in the Tancheng-Lujiang fault zone．