The Yutian earthquake with MS 7. 3 happened on February 12,2014 and the causative structure is Altun fault. The intensity of meizoseismal area is Ⅸ degree which in depopulated area. The 216 investigation points covered the area with intensity of Ⅵ,Ⅶ degree. The building,municipal facilities,traffic facilities and agriculture of about seven cities,thirty nine villages were destroyed to different degrees in Hotan and Bayinguoleng Mongolian Autonomous Prefecture. The seismic hazard were influenced by site conditions in a large area because this earthquake was closer to the basin than the Yutian earthquake with MS7. 3 in 2008.