On the platform of ArcGIS，this paper researches on the spatial distribution of seismic stations in Shandong Province based on overlay and buffer analysis of seismic stations，administrative zoning map，active fault zone and seismic acceleration zoning map. The conclusion shows the nonuniform distribution of seismic stations in Shandong Province：nearly half the seismic stations are within 6km of the active faults，most of them are within 25km，and more than 60% of the seismic stations are within the area of seismic intensity Ⅶ on the seismic zoning map.