The Air-gun source has many advantages：economical and environmental protection and excellent repetition. The method has been used to study changes of the subsurface structure in recent years，and there are a lot of achievements. In order to explore the ability on imaging crust structure using active air-gun source，we conducted an experiment along the Yangzte River from Ma'anshan to Anqing segment using offshore air-gun source(the Anhui experiment). 2973 shots and 1872air-gun shots were excited at twenty fixed points and were received by 109 permanent stations and 700 mobile stations(11 lines). Air-gun source can form motivating and observational network densely with the accurate origin time and position. Compare with explosive source，air-gun has a very clear S phase. Thus，air-gun source can reduce the source location error in tomography，and can take full advantage of direct and later phases. To get the crust velocity structure in the southern tip of Tan-Lu fault，we used the data received by permanent stations in the Anhui air-gun experiment to pick P phase，and make tomography by 20air-gun sources,52 permanent stations，and 335 phases. We got a very good preliminary result of P wave velocity and verified the possibility to make tomography using air-gun source: (1)The use of high-capacity air-gun can make 3D body wave tomography. (2)Image of 15km depth shows the clear velocity anomaly outline，which is related to the geological tectonic background with prominent heterogeneity in transverse. (3)The Qinling-Dabie orogenic belt shows high velocity，which is associated with the ultrahigh-pressure metamorphic rocks in depth region，while the Yangtze River region presents low velocity anomaly，corresponding to the special background of mineralization.