We systematically collected and analyzed the historic earthquake record and site investigation of the southern Tianshui M6.0 earthquake in 1936,checked the intensities of the destroyed sites and investigation points and modified the seismic isoseismal lines. The result shows that the epicenter area was located in the region north to Tianshui County and the maximum intensity of the earthquake is Ⅷ. The long axis of the meizoseismal area is about the NEE direction and almost overlapped to the middle segment of Lixian-Luojiabu active fault,which means the fault should be the seismogenic structure of the earthquake. Due to the effect of the north margin fault zone of the west Qinling,Liupanshan fault zone and loess plateau in the north region,the long axis direction of isoseismal line with lower intensity offsets counter-clockwise and the attenuation of intensity and ground motion slows down in the north direction,which causes the asymmetry of the isoseismal lines from south to north. In view of the uncertainty of the study of historic strong earthquake and active tectonic in this region,the research achievement of the southern Tianshui M6.0 earthquake in 1936 has important referential value.