The genetic of earthquake is complicate;the observation technique is limited, and the relationship between different observed anomaly and the subsequent earthquake is uncertain. Therefore, probabilistic expression of predictions is a scientific and appropriate approach. In this paper, we calculate the probabilistic prediction results in the risk area suggested by the single prediction method(such as seismicity, underground fluid, deformation, electromagnetic, etc.), taking account of the background earthquake recurrence probability and the forecast efficiency of the corresponding prediction method based on the Bayesian Formula. Then we calculate the earthquake risk probability based on different prediction method by utilizing the comprehensive probability analysis method. In 2018, from February to September, we calculated the probabilistic earthquake prediction for the next every 3 months and for the every 3 months in the next year. Short-term prediction result shows that about 75% earthquakes(M_S ≥ 5.0) in Chinese Mainland are distributed in the relative high probability region.