Using waveforms from the China Seismic Array,we calculated the apparent stress of 105 earthquakes with 1.5 ≤ M_L ≤ 3.3 within 80km radius of the epicenter about 2 years before the Menyuan M_S6.4 earthquake in 2016. The results show that,apparent stress between January 13,2015 to January 20,2016 was obviously high than that between March 23,2014 to January 12,2015,and apparent stress increased obviously about 1-year before the Menyuan M_S6.4 earthquake and decreased significantly,finally increased again about 2 months before the Menyuan M_S6.4 earthquake. We used the normalized apparent stress to deduct the effect of magnitude. The comparison of the normalized apparent stress of the two periods show that the stress level of the study area increased about 1-year before the Menyuan M_S6.4 earthquake. Spatial distribution of the normalized apparent stress shows that,the Huangcheng-Shuangta fault was a high value anomaly area which appeared 48km away from the epicenter of Menyuan M_S6.4 earthquake. The abnormals of apparent stress,Pingan water level and Ledu gas radon show a good corresponding relation with the increase of stress field and was a good seismometry and precursory earthquake case with significant anomaly. The abnormal of apparent stress can judge stress level and define anomaly area. Annual variation of precursory can judge the urgency of time,and therefore using seismometry and precursory anomaly together can make earthquake prediction to a certain extent.