In this paper, we apply the waveform analysis and inversion to determine the apparent stresses of the 2017 Jiuzhaigou M_S7.0 earthquake sequence by using the digital seismic waveform from the China Digital Seismograph Network. The main conclusions are:① The apparent stress of the Jiuzhaigou earthquake sequence was at relative high level in the early stage, and began to decrease in less than a day after the main shock. The apparent stress is at a stable level after the first week since the main shock, although the apparent stress curve had a slight fluctuation. ② The apparent stress showed temporal and spatial differences, the apparent stress level in the southeast section decreased more rapidly than the northwest section, and the mean apparent stress level in the southeast section was slightly higher than or equal to the northwest section in the early stage;while from the largest aftershock to 70 days after the main shock, the stress level in the northwest section was higher than the southeast section, which might be related to the more full rupture of the southeast section than the northwest section. ③ The largest aftershock occurred on the southeast side of the main shock, where the apparent stress was at a relative high level. The aftershocks of high apparent stress were nearly located at the both ends of the source areas, which was consistent with the relative concentration of the stress at these areas under the bilateral expansion of the main shock.